Remission of eczema and recovery of Th1 polarization following treatment with Dupilumab in STAT3 hyper IgE syndrome

Pediatr Allergy Immunol. 2022 Apr;33(4):e13770. doi: 10.1111/pai.13770.
No abstract available

Keywords: Dupilumab; HIES; STAT3; Th1; Th2; hyper IgE syndrome; immunodeficiency; job syndrome.

Publication types

  • Letter

MeSH terms

  • Antibodies, Monoclonal, Humanized / therapeutic use
  • Eczema* / drug therapy
  • Humans
  • Job Syndrome* / drug therapy
  • Mutation
  • STAT3 Transcription Factor / genetics

Substances

  • Antibodies, Monoclonal, Humanized
  • STAT3 Transcription Factor
  • STAT3 protein, human
  • dupilumab