Unusual initial manifestation of choroidal melanoma in a 46-year-old adult with rapid growth over 9 months

Olga Furashova; Katrin Engelmann; Antonia M Joussen; Aline I Riechardt

doi:10.1016/j.ajoc.2022.101518

Unusual initial manifestation of choroidal melanoma in a 46-year-old adult with rapid growth over 9 months

Am J Ophthalmol Case Rep. 2022 Apr 12:26:101518. doi: 10.1016/j.ajoc.2022.101518. eCollection 2022 Jun.

Authors

Olga Furashova¹, Katrin Engelmann¹, Antonia M Joussen², Aline I Riechardt²

Affiliations

¹ Department of Ophthalmology, Klinikum Chemnitz gGmbH, Flemmingstrasse 2, 09116, Chemnitz, Germany.
² Department of Ophthalmology, Charité - Universitätsmedizin Berlin, Berlin, Germany.

Abstract

Purpose: To report a case with unusual initial manifestation of uveal melanoma in a 46-year-old adult.

Observations: A 46-year-old man demonstrated a mid-peripheral temporal partially hyperpigmented lesion in his left eye. Initial clinical appearance as well as multimodal imaging approaches were similar to a chorioretinitic disease. Over the course of 9 months, a massive tumor growth and exudative retinal detachment could be observed. The diagnosis of choroidal melanoma was histopathologically confirmed after endoresection.

Conclusions and importance: Classical choroidal melanoma manifest as pigmented, prominent tumors with >2 mm tumor thickness, exudative retinal detachment, and orange pigment. In our case, none of these classical clinical characteristic signs of melanoma were present at initial presentation, but the tumor underwent progressive development with significant tumor growth and exudative retinal detachment during the following 9 months.

Keywords: Choroidal melanoma; Masquerade syndrome; Unusual manifestation; Uveal melanoma.

Publication types

Case Reports