Chemotherapy Combined With Surgery in a Case With Metanephric Adenoma

Shaohua Hu; Zhenli Zhao; Zhisheng Wan; Weizhen Bu; Songqiang Chen; Yiqun Lu

doi:10.3389/fped.2022.847864

Chemotherapy Combined With Surgery in a Case With Metanephric Adenoma

Front Pediatr. 2022 Apr 7:10:847864. doi: 10.3389/fped.2022.847864. eCollection 2022.

Authors

Shaohua Hu¹, Zhenli Zhao¹, Zhisheng Wan¹, Weizhen Bu¹, Songqiang Chen¹, Yiqun Lu²

Affiliations

¹ Department of Urology, Hainan Women and Children's Medical Center, Haikou, China.
² Department of Urology, Children's Hospital of Fudan University, Shanghai, China.

Abstract

Background: Metanephric adenoma is an extremely rare renal neoplasm, especially in pediatrics. Chemotherapy combined with surgery in metanephric adenoma has not been reported.

Methods: We describe a case of metanephric adenoma in a child less than 2 years old, which were treated by chemotherapy combined with surgery.

Results: Nephron sparing surgery was performed after regular chemotherapy, and the pathological result was metanephric adenoma.

Conclusion: Pediatric metanephric adenoma is extremely rare; the clinical manifestations and imaging examinations lack specificity. Nephron sparing surgery is recommended as the preferred treatment for metanephric adenoma. Long-term follow-up and more in-depth molecular genetic research are still needed to determine the benign or malignant of metanephric adenoma and whether chemotherapy drugs have an effect on it.

Keywords: chemotherapeutics; children; metanephric adenoma; nephron sparing surgery; operation treatment.