Severe post-gastric bypass hypoglycemia in pregnancy

Tal Schiller; Alena Kirzhner; Taiba Zornitzki; Lee Cohen; Yael Winter Shafran; Viviana Ostrovsky; Hilla Knobler; Edi Vaisbuch

doi:10.1016/j.orcp.2022.04.003

Severe post-gastric bypass hypoglycemia in pregnancy

Obes Res Clin Pract. 2022 May-Jun;16(3):272-275. doi: 10.1016/j.orcp.2022.04.003. Epub 2022 Apr 19.

Authors

Tal Schiller¹, Alena Kirzhner², Taiba Zornitzki², Lee Cohen², Yael Winter Shafran³, Viviana Ostrovsky², Hilla Knobler², Edi Vaisbuch³

Affiliations

¹ Diabetes, Endocrinology and Metabolic Disease Institute, Kaplan Medical Center, Rehovot, Israel, and Faculty of Medicine, Hebrew University of Jerusalem, Israel. Electronic address: talsc1@clalit.org.il.
² Diabetes, Endocrinology and Metabolic Disease Institute, Kaplan Medical Center, Rehovot, Israel, and Faculty of Medicine, Hebrew University of Jerusalem, Israel.
³ Obstetric and Gynecology Department, Kaplan Medical Center, Rehovot, Israel, and Faculty of Medicine, Hebrew University of Jerusalem, Israel.

PMID: 35459630
DOI: 10.1016/j.orcp.2022.04.003

Abstract

Post-bariatric surgery hypoglycemia (PBH) is a serious and relatively prevalent complication of bariatric surgery and is often underdiagnosed due to unawareness. PBH can have a profound effect on health and quality of life. Data regarding the natural history and management of PBH during pregnancy are lacking. Here we describe a case of a 34-year-old woman who presented with intractable PBH during the second trimester of her third pregnancy, three years after a Roux-en-Y gastric bypass (RYGB). Treatment with nifedipine showed partial response and eventually intravenous (IV) glucose was needed until birth.

Keywords: Hypoglycemia; Obesity; Post-bariatric surgery hypoglycemia; Pregnancy; Roux-en-Y Gastric Bypass.

Publication types

Case Reports

MeSH terms

Adult
Bariatric Surgery* / adverse effects
Female
Gastric Bypass* / adverse effects
Glucose
Humans
Hypoglycemia* / diagnosis
Hypoglycemia* / etiology
Obesity, Morbid* / complications
Obesity, Morbid* / surgery
Pregnancy
Quality of Life

Substances

Glucose