Effects of SARS-CoV-2 Inflammation on Selected Organ Systems of the Human Body

Int J Mol Sci. 2022 Apr 10;23(8):4178. doi: 10.3390/ijms23084178.

Abstract

Introduction and purpose of the study: SARS-CoV-2 virus does not only affect the respiratory system. It may cause damage to many organ systems with long-term effects. The latest scientific reports inform that this virus leaves a long-term trace in the nervous, circulatory, respiratory, urinary and reproductive systems. It manifests itself in disturbances in the functioning of the organs of these systems, causing serious health problems. The aim of the study was to review the latest research into the long-term effects of COVID-19 and determine how common these symptoms are and who is most at risk. Based on a literature review using the electronic scientific databases of PubMed and Web of Science on the long-term effects of SARS-CoV-2 infection, 88 studies were included in the analysis. The information contained in the analyzed literature shows that the SARS-CoV-2 virus can cause multi-organ damage, causing a number of long-term negative health complications.

Conclusions: There is evidence that the virus can cause long-term complications lasting more than six months. They mainly concern disturbances in the functioning of the nervous, circulatory and respiratory systems. However, these studies are small or short-lasting, and many are speculative.

Keywords: COVID-19; human body; long-term effects; multi-organ damage.

Publication types

  • Review

MeSH terms

  • COVID-19*
  • Human Body
  • Humans
  • Inflammation
  • SARS-CoV-2*