Genetic study with 21 autosomal STRs in five Peruvian macro regions for human identification purposes

María E Bermejo Valladolid; Jianye Ge; Bruce Budowle; Cesar Infante Valdez; Carlos David Neyra-Rivera

doi:10.1016/j.legalmed.2022.102073

Genetic study with 21 autosomal STRs in five Peruvian macro regions for human identification purposes

Leg Med (Tokyo). 2022 Jul:57:102073. doi: 10.1016/j.legalmed.2022.102073. Epub 2022 Apr 15.

Authors

María E Bermejo Valladolid¹, Jianye Ge², Bruce Budowle³, Cesar Infante Valdez⁴, Carlos David Neyra-Rivera⁵

Affiliations

¹ Posgrado de Ciencias Biológicas, Universidad Nacional Mayor de San Marcos, Ciudad Universitaria Cercado de Lima, Lima, Peru; Unidad de Biología Molecular y de Genética (UNBIMOG), Instituto de Medicina Legal y Ciencias Forenses del Ministerio Público, Lima, Peru.
² Center for Human Identification, University of North Texas Health Science Center, Ft Worth, TX 76107, USA.
³ Consultant, Christiansburg, VA 24073, USA.
⁴ Unidad de Biología Molecular y de Genética (UNBIMOG), Instituto de Medicina Legal y Ciencias Forenses del Ministerio Público, Lima, Peru.
⁵ Universidad Privada Peruano Alemana, Lima, Peru; Escuela de Posgrado, Universidad Privada Norbert Wiener, Lima, Peru. Electronic address: carlosdavidmp@outlook.es.

PMID: 35453076
DOI: 10.1016/j.legalmed.2022.102073

Abstract

In this population study 1541 samples in total were collected and analyzed. The samples were collected from five jurisdictions: North macro region (n = 272), Central macro region (n = 404), South macro region (n = 272), East macro region (n = 197), and the Lima macro region (n = 396). The samples were analyzed using the Investigator 24 plex GO and Investigator 24 plex QS kits which enable typing of 21 autosomal STR loci and an amelogenin marker for sex determination. The combined power of discrimination and the combined probability of exclusion for the total population were 0.9999999999 and 0.99999978, respectively. These population geographic subgroupings are similar, supporting that the combined Peruvian data or individual subgroupings could be used for generating statistics in forensic casework.

Keywords: Autosomal STRs; Forensic genetics; Genetic distance; Human identification; Peruvian population.

MeSH terms

Amelogenin / genetics
DNA Fingerprinting
Forensic Anthropology
Forensic Genetics*
Gene Frequency
Genetics, Population
Humans
Microsatellite Repeats* / genetics
Peru

Substances

Amelogenin