Inhibiting U1 telescripting: A means to an end for transcription

Audrey Yi Tyan Peng; Brian C Freeman

doi:10.1016/j.molcel.2022.04.001

Inhibiting U1 telescripting: A means to an end for transcription

Mol Cell. 2022 Apr 21;82(8):1405-1407. doi: 10.1016/j.molcel.2022.04.001.

Authors

Audrey Yi Tyan Peng¹, Brian C Freeman²

Affiliations

¹ Department of Cell and Developmental Biology, University of Illinois, Urbana-Champaign, Urbana, IL 61801, USA.
² Department of Cell and Developmental Biology, University of Illinois, Urbana-Champaign, Urbana, IL 61801, USA. Electronic address: bfree@illinois.edu.

Abstract

In this issue of Molecular Cell, Cugusi et al. (2022) discover that inhibition of U1 telescripting is a novel mechanism that promotes a switch between gene programs in response to heat stress.

Published by Elsevier Inc.

Grants and funding

R35 GM136660/GM/NIGMS NIH HHS/United States