Flavonoids: A Reservoir of Drugs from Nature

Mini Rev Med Chem. 2023;23(7):772-786. doi: 10.2174/1389557522666220420102545.

Abstract

Flavonoids are associated with many plants and dietary foods; their chemical study has always attracted the interest of chemists working in the area of natural products and synthetic chemistry. Research in phytochemistry has produced many useful drugs. The analogs of flavonoids exhibit anticancer, anti-tuberculosis, anti-diabetic, antiviral, antibacterial, antioxidant, anti-inflammatory, antiproliferative, anti-spermatogenic, and antipsychotic activities. This review article highlights flavonoids' significance and medicinal application and displays a comparative overview of the biological activities of flavonoids and flavonoid derivatives. It covers almost all necessary reports for future directions in drug discovery.

Keywords: Flavones; anti-inflammatory; anticancer activity; antioxidants; antiviral drugs; natural products.

Publication types

  • Review

MeSH terms

  • Anti-Bacterial Agents*
  • Anti-Inflammatory Agents
  • Antioxidants / pharmacology
  • Antiviral Agents / pharmacology
  • Flavonoids* / pharmacology
  • Plants

Substances

  • Flavonoids
  • Anti-Bacterial Agents
  • Anti-Inflammatory Agents
  • Antiviral Agents
  • Antioxidants