OK-432 Treatment of Ranula Intruding into the Cervical Region

Nobuo Ohta; Shion Shirane; Shigeru Fukase; Rei Kawata; Teruyuki Sato; Nozomi Satani; Takahiro Suzuki

doi:10.3390/clinpract12020025

OK-432 Treatment of Ranula Intruding into the Cervical Region

Clin Pract. 2022 Mar 28;12(2):215-218. doi: 10.3390/clinpract12020025.

Authors

Nobuo Ohta¹, Shion Shirane¹, Shigeru Fukase², Rei Kawata¹, Teruyuki Sato¹, Nozomi Satani³, Takahiro Suzuki¹

Affiliations

¹ Division of Otolaryngology, Tohoku Medical and Pharmaceutical University Hospital, 1-12-1, Fukumuro, Miyaginoku, Sendai 983-8512, Japan.
² Fukase Clinic, 2-7-30, Nanokamachi, Yamagata 990-0042, Japan.
³ Division of Radiology, Tohoku Medical and Pharmaceutical University Hospital, 1-12-1, Fukumuro, Miyaginoku, Sendai 981-8512, Japan.

Abstract

Objectives: Plunging ranula intruding into the cervical region is rare and a standard therapy has not yet been consolidated. This paper investigates the outcomes and side effects of OK-432 treatment in patients with a ranula extending into the cervical region.

Methods: The study design and setting consisted of a planned data collection at Tohoku Medical and Pharmaceutical University and Fukase Clinic. Eight patients with ranula extending into the cervical region received OK-432 treatment between January 2016 and February 2019. OK-432 treatment was performed for patients with ranula extending into the cervical region.

Results: In all patients, a total shrinkage and marked reduction in lesions were observed without local scars or deformations after OK-432 treatment. Complications were local swelling and mild fever (37.5-38.5 °C), which lasted a few days in half of the patients.

Conclusions: OK-432 treatment is straightforward, secure, and efficacious and can be substituted for surgery in the treatment of ranula extending into the cervical region.

Keywords: OK-432; anterior cervical region; ranula.