Givosiran Likely Inhibits Cytochrome P450 More Substantially Than Reported

Clin Pharmacol Ther. 2022 Jul;112(1):24. doi: 10.1002/cpt.2597. Epub 2022 Apr 21.

Authors

Sander Bins¹, Eliane Sardh², Janneke G Langendonk¹

Affiliations

¹ Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
² Karolinska University Hospital, Stockholm, Sweden.

PMID: 35446989
DOI: 10.1002/cpt.2597

No abstract available

Publication types

Letter

MeSH terms

Acetylgalactosamine* / analogs & derivatives
Cytochrome P-450 Enzyme System*
Humans
Pyrrolidines

Substances

Pyrrolidines
Cytochrome P-450 Enzyme System
Acetylgalactosamine
givosiran