[A Case Report for Peritoneal Recurrences by Laparoscopic Surgery after Colorectal Cancer Resection]

Gan To Kagaku Ryoho. 2022 Apr;49(4):489-491.
[Article in Japanese]

Abstract

We report a cases report of colorectal cancer who underwent repeated resection for peritoneal recurrences by laparoscopic surgery. In 2013, a 70-year-old woman diagnosed with an ascending colon cancer underwent laparoscopic right hemicolectomy. The pathological diagnosis was tub2, pT4aN1M0, Stage Ⅲb. Postoperative adjuvant chemotherapy(uracil and tegafur/Leucovorin)was administered. PET-CT performed at 25 months after the surgery because of CEA elevation. It revealed a peritoneal recurrence in the pouch of Douglas. The following peritoneal recurrences were removed by laparoscopic Hartmann's procedure. Chemotherapy(5-fluorouracil/levofolinate/oxaliplatin/bevacizumab)was administered 11 courses and after that chemotherapy(5-fluorouracil/levofolinate/bevacizumab)was administered 6 courses. PET-CT performed 37 months after the second surgery revealed a peritoneal recurrence near the right ovary in the pouch of Douglas. The following peritoneal recurrences was removed. Chemotherapy(tegafur/gimeracil/oteracil/bevacizumab)was administered 11 courses. The long-term survival has been continued for 7 years and 7 months after first operation. It was considered that laparoscopic surgery for peritoneal recurrence in colorectal cancer is contributed to one of the surgical procedures in selected patients.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Bevacizumab / therapeutic use
  • Colonic Neoplasms* / surgery
  • Colorectal Neoplasms* / drug therapy
  • Colorectal Neoplasms* / pathology
  • Colorectal Neoplasms* / surgery
  • Female
  • Fluorouracil / therapeutic use
  • Humans
  • Laparoscopy*
  • Leucovorin / therapeutic use
  • Peritoneal Neoplasms* / drug therapy
  • Peritoneal Neoplasms* / surgery
  • Positron Emission Tomography Computed Tomography
  • Recurrence
  • Tegafur / therapeutic use

Substances

  • Tegafur
  • Bevacizumab
  • Leucovorin
  • Fluorouracil