Legionella micdadei Aquaticum Infection: a Case Report and Literature Review

Clin Lab. 2022 Apr 1;68(4). doi: 10.7754/Clin.Lab.2021.210725.

Abstract

Background: The goal of the study was to analyze the clinical characteristics of Legionella cases caused by Legionella micdadei and explore the diagnosis and treatment.

Methods: The pathogen was identified by routine isolation and culture, biochemical identification, serum agglutination test, mass spectrometry identification, and routine PCR. Combined with the related literature review, the clinical diagnosis and treatment of Legionella micdadei were analyzed.

Results: The patient suffered from pulmonary infection caused by Legionella micdadei. After treatment with moxi-floxacin for 2 weeks, the body temperature dropped and the shadow of the lung was completely absorbed after 2 months. Combined with literature analysis, 8 cases of Legionella micetidis, including 7 males and 1 female, aged from 27 to 57 years old, 6 cases with basic diseases, which were treated with azithromycin, erythromycin or levofloxacin, and all of them achieved good therapeutic effect.

Conclusions: The detection of Legionella should be strengthened in patients with pneumonia whose symptoms have no obvious improvement after antibiotic treatment. Azithromycin, erythromycin or levofloxacin are effective in the treatment of Legionella spp.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Azithromycin / pharmacology
  • Azithromycin / therapeutic use
  • Erythromycin / pharmacology
  • Female
  • Humans
  • Legionella*
  • Legionellaceae
  • Legionellosis* / complications
  • Legionellosis* / diagnosis
  • Legionellosis* / drug therapy
  • Levofloxacin / pharmacology
  • Levofloxacin / therapeutic use
  • Male
  • Middle Aged
  • Pneumonia* / diagnosis

Substances

  • Erythromycin
  • Levofloxacin
  • Azithromycin

Supplementary concepts

  • Tatlockia micdadei