Type 2 Diabetes Mellitus with HbJ trait: A management conundrum

Malays Fam Physician. 2022 Mar 7;17(1):86-89. doi: 10.51866/cr1288. eCollection 2022 Mar 28.

Abstract

Optimal glycaemic control is crucial in patients with diabetes mellitus (DM) to avoid episodes of hypoglycaemia and both micro- and macrovascular complications. Diabetic control relies mainly on the evaluation of haemoglobin A1c (HbA1c), which is unfortunately unreliable in patients with haemoglobinopathies. This case report describes a patient with type 2 DM and haemoglobin J (HbJ) trait, which resulted in erratic HbA1c values throughout her follow-up. Other approaches, such as self-blood glucose monitoring, are needed to evaluate glycaemic control instead of relying on HbA1c alone to guide the management DM in these patients.

Keywords: HbA1c; HbJ trait; haemoglobinopathy.

Publication types

  • Case Reports