Biotinylated magnetic molecularly imprinted polymer nanoparticles for cancer cell targeting and controlled drug delivery

Chem Commun (Camb). 2022 May 5;58(37):5642-5645. doi: 10.1039/d2cc00740a.

Abstract

Here, multivalent functions have been successfully integrated on a single core-shell type nanostructure, for remote-controlled and receptor-targeted intracellular delivery of doxorubicin (DOX) to breast cancer cells that overexpress biotin receptors.

MeSH terms

  • Cell Line, Tumor
  • Doxorubicin / chemistry
  • Drug Delivery Systems
  • Magnetic Phenomena
  • Molecularly Imprinted Polymers
  • Nanoparticles* / chemistry
  • Neoplasms* / drug therapy

Substances

  • Molecularly Imprinted Polymers
  • Doxorubicin