Laninamivir-induced ischemic enterocolitis: A case report

World J Clin Cases. 2022 Mar 26;10(9):2864-2870. doi: 10.12998/wjcc.v10.i9.2864.

Abstract

Background: Neuraminidase inhibitor-associated acute hemorrhagic colitis is rare. We report a case of ischemic enterocolitis that was likely caused by laninamivir.

Case summary: A 54-year-old female patient with influenza type A was administered 40 mg of laninamivir via inhalation once. On the same day, the patient experienced bloody stools and lower abdominal pain. A contrast-enhanced abdominal computed tomography showed edema-like changes from the descending colon to the sigmoid colon, which suggested ischemic enterocolitis.

Conclusion: We treated a patient with ischemic enterocolitis caused by laninamivir, a rare but similar symptom following the administration of oseltamivir.

Keywords: Case report; Hemorrhagic colitis; Influenza; Ischemic enterocolitis; Laninamivir; Neuraminidase inhibitor.

Publication types

  • Case Reports