Effectiveness of Different Algorithms and Cut-off Value in Preeclampsia First Trimester Screening

J Pregnancy. 2022 Apr 8:2022:6414857. doi: 10.1155/2022/6414857. eCollection 2022.

Abstract

Results: For the cut-off point >1 : 150, 86 women at an increased risk of eo-PE using algorithm 1 were identified. Of these 86 patients, 83 (96%) were identified using algorithm 2, 62 (72%) using algorithm 3, and 60 (69%) using algorithm 4. In addition, it was demonstrated that between 21% and 29% of women at a low risk of eo-PE could be given acetylsalicylic acid if a screening test was used that did not account for PlGF.

Conclusions: In order to provide the highest level of health care to pregnant women, it is extremely important that full screening for eo-PE should be ensured. The cheapest algorithm based only on MAP and UtPI resulted in our patients being unnecessarily exposed to complications.

MeSH terms

  • Algorithms
  • Biomarkers
  • Female
  • Humans
  • Mass Screening / methods
  • Placenta Growth Factor
  • Pre-Eclampsia* / diagnosis
  • Pre-Eclampsia* / prevention & control
  • Pregnancy
  • Pregnancy Trimester, First

Substances

  • Biomarkers
  • Placenta Growth Factor