Regulation of Social Recognition Memory in the Hippocampal Circuits

Xinnian Wang; Yang Zhan

doi:10.3389/fncir.2022.839931

Regulation of Social Recognition Memory in the Hippocampal Circuits

Front Neural Circuits. 2022 Mar 30:16:839931. doi: 10.3389/fncir.2022.839931. eCollection 2022.

Authors

Xinnian Wang^{1

2}, Yang Zhan^{1

3}

Affiliations

¹ Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences (CAS), Shenzhen, China.
² Division of Life Sciences and Medicine, School of Life Sciences, University of Science and Technology of China, Hefei, China.
³ Guangdong Provincial Key Laboratory of Brain Connectome and Behavior, CAS Key Laboratory of Brain Connectome and Manipulation, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research Institutions, Shenzhen, China.

Abstract

Social recognition memory reflects the ability of the social animals to recognize and remember familiar individuals of the same species. The unique ability for mammals to recognize conspecifics is essential and beneficial when animals conduct daily social activities. This brief review summarizes a brain network underlying social recognition memory and explores the possible relationships between social isolation and social recognition memory. Finally, we introduce some possible related molecular mechanisms underlying social recognition memory. These findings help us explore potential targeting brain areas or circuits of social communication disorder.

Keywords: dorsal CA2; oxytocin; social isolation; social recognition memory; ventral CA1.

Publication types

Review
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Brain
Hippocampus* / physiology
Mammals
Recognition, Psychology* / physiology
Social Behavior