Nanomaterials and metal-organic frameworks for biosensing applications of mutations of the emerging viruses

Anal Biochem. 2022 Jul 1:648:114680. doi: 10.1016/j.ab.2022.114680. Epub 2022 Apr 14.

Abstract

The world today lives in a state of terrible fear due to the mutation of the emerging COVID-19. With the continuation of this pandemic, there is an urgent need for fast, accurate testing devices to detect the emerging SARS-CoV-2 pandemic in terms of biosensors and point-of-care testing. Besides, the urgent development in personal defense tools, anti-viral surfaces and wearables, and smartphones open the door for simplifying the self-diagnosis process everywhere. This review introduces a quick COVID-19 overview: definition, transmission, pathophysiology, the identification and diagnosis, mutation and transformation, and the global situation. It also focuses on an overview of the rapidly advanced technologies based on nanomaterials and MOFs for biosensing, diagnosing, and viral control of the SARS-CoV-2 pandemic. Finally, highlight the latest technologies, applications, existing achievements, and preventive diagnostic strategies to control this epidemic and combat the emerging coronavirus. This humble effort aims to provide a helpful survey that can be used to develop a creative solution and to lay down the future vision of diagnosis against COVID-19.

Keywords: Antiviral wearable; COVID-19; Metal-organic frameworks; Nanomaterials; POCT; Smartphone nano-biosensor.

Publication types

  • Review

MeSH terms

  • Biosensing Techniques*
  • COVID-19* / diagnosis
  • Humans
  • Metal-Organic Frameworks*
  • Mutation
  • Nanostructures*
  • SARS-CoV-2 / genetics
  • Viruses*

Substances

  • Metal-Organic Frameworks