Highly efficient synthesis of 3,4-diarylbutadiene sulfones using Heck-Matsuda reaction

Olga V Shurupova; Sergey A Rzhevskiy; Lidiya I Minaeva; Maxim A Topchiy; Andrey F Asachenko

doi:10.1039/d2ra00078d

Highly efficient synthesis of 3,4-diarylbutadiene sulfones using Heck-Matsuda reaction

RSC Adv. 2022 Feb 15;12(9):5517-5521. doi: 10.1039/d2ra00078d. eCollection 2022 Feb 10.

Authors

Olga V Shurupova¹, Sergey A Rzhevskiy¹, Lidiya I Minaeva¹, Maxim A Topchiy¹, Andrey F Asachenko¹

Affiliation

¹ A.V. Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences Leninsky Prospect 29 Moscow 119991 Russia aasachenko@ips.ac.ru.

Abstract

For the first time we describe a general method for the synthesis of previously not synthesized unsymmetrical 3,4-diarylbutadiene sulfones which can be stable convenient precursors for 2,3-diaryl-1,3-butadienes. Our method for arylation of butadiene sulfones via Heck-Matsuda reaction allows to obtain unsymmetrical 3,4-diarylbutadiene sulfones with a variety of alkyl, alkoxy, nitro, ethoxycarbonyl, perfluoroalkyl and halogen substituents (30 examples) in very good yields using readily available reagents and catalysts.