Guaiane sesquiterpenes from the gorgonian Echinogorgia flora collected in the South China Sea

Xiangchao Luo; Rongcui Wu; Xiao Han; Xuli Tang; Qi Wang; Pinglin Li; Guoqiang Li

doi:10.1039/d1ra08631f

Guaiane sesquiterpenes from the gorgonian Echinogorgia flora collected in the South China Sea

RSC Adv. 2022 Jan 19;12(5):2662-2667. doi: 10.1039/d1ra08631f. eCollection 2022 Jan 18.

Authors

Xiangchao Luo^{1

2}, Rongcui Wu^{1

2}, Xiao Han^{1

2}, Xuli Tang³, Qi Wang^{1

2

4}, Pinglin Li^{1

2}, Guoqiang Li^{1

2}

Affiliations

¹ Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China Qingdao 266003 People's Republic of China luoxc981@163.com.
² Laboratory of Marine Drugs and Biological Products, Pilot National Laboratory for Marine Science and Technology Qingdao 266235 People's Republic of China.
³ College of Chemistry and Chemical Engineering, Ocean University of China Qingdao 266100 People's Republic of China.
⁴ Department of Natural Medicinal Chemistry and Pharmacognosy, School of Pharmacy, Qingdao University Qingdao 266021 People's Republic of China.

Abstract

Echinoflorine (1), a new dimethylamino-substituted guaipyridine alkaloid with a novel γ-lactone-cyclohepta[c]pyridine fused skeleton, and three new guaiane sesquiterpene lactones, echinofloranolides A-C (2-4), together with eight known guaiane sesquiterpenes were isolated from the gorgonian Echinogorgia flora collected in the South China Sea. Their structures were elucidated by 1D and 2D NMR, HRESIMS, calculated ECD and DP4+ probability analyses.