Graphdiyne nanosheets as a platform for accurate copper(ii) ion detection via click chemistry and fluorescence resonance energy transfer

Chenchen Ge; Jiaofu Li; Dou Wang; Kongpeng Lv; Quan Liu; Yan Shen; Xiaoqing Zhuang; Wankun Luo; Zongze Wu; Yuhua Zhang; Lulin Shi; Liping Liu; Shiyun Bao; Han Zhang

doi:10.1039/d0ra08595b

Graphdiyne nanosheets as a platform for accurate copper(ii) ion detection via click chemistry and fluorescence resonance energy transfer

RSC Adv. 2021 Jan 28;11(10):5320-5324. doi: 10.1039/d0ra08595b.

Authors

Chenchen Ge^{1

2}, Jiaofu Li³, Dou Wang⁴, Kongpeng Lv¹, Quan Liu¹, Yan Shen¹, Xiaoqing Zhuang¹, Wankun Luo¹, Zongze Wu¹, Yuhua Zhang¹, Lulin Shi¹, Liping Liu¹, Shiyun Bao¹, Han Zhang³

Affiliations

¹ Department of Hepatobiliary and Pancreatic Surgery, The Second Clinical Medical College, Jinan University (Shenzhen People's Hospital) Shenzhen 518020 China bao.shiyun@szhospital.com liu.liping@szhospital.com.
² College of Health Science and Environmental Engineering, Shenzhen Technology University Shenzhen 518118 China.
³ Institute of Microscale Optoelectronics, Collaborative Innovation Centre for Optoelectronic Science & Technology, Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, Guangdong Laboratory of Artificial Intelligence and Digital Economy (SZ), Shenzhen University Shenzhen 518060 PR China hzhang@szu.edu.cn.
⁴ Department of Biomedical Engineering, Southern University of Science and Technology Shenzhen 518055 China.

Abstract

A novel sensing platform for sensitive detection of copper(ii) ions (Cu²⁺) in living cells and body fluids was developed by taking advantage of the excellent fluorescence quenching ability of graphdiyne (GDY) and the high specificity of click chemistry for the first time.