The role of COVID-19 in prostate tissue inflammation: first pathological evidence

Prostate Cancer Prostatic Dis. 2022 Feb;25(2):370-372. doi: 10.1038/s41391-022-00542-5. Epub 2022 Apr 14.

Abstract

According to current studies, COVID-19 might have an impact on semen quality. Therefore, SARS-CoV-2 may affect other traits of male reproductive system, including the prostate. Thus, we recruited patients who experienced COVID-19 infection in-between prostate biopsy and radical prostatectomy and compared prostate samples inflammation, measured with IRANI score, to those who did not. Indeed, we recruited 20 patients, aged 69 (62-73) years, finding no difference between the 10 patients with COVID-19 infection and the others in IRANI score and all its sub-scores. Hence, according to our exploratory and limited results, COVID-19 infection might have no gross effect on prostate inflammation.

MeSH terms

  • COVID-19*
  • Humans
  • Inflammation / pathology
  • Male
  • Prostate / pathology
  • Prostate / surgery
  • Prostatectomy
  • Prostatic Neoplasms* / pathology
  • Prostatitis* / complications
  • Prostatitis* / pathology
  • SARS-CoV-2
  • Semen Analysis