Consolidated bioprocessing of lignocellulosic biomass: Technological advances and challenges

Reeta Rani Singhania; Anil Kumar Patel; Anusuiya Singh; Dibyajyoti Haldar; Shveta Soam; Chiu-Wen Chen; Mei-Ling Tsai; Cheng-Di Dong

doi:10.1016/j.biortech.2022.127153

Consolidated bioprocessing of lignocellulosic biomass: Technological advances and challenges

Bioresour Technol. 2022 Jun:354:127153. doi: 10.1016/j.biortech.2022.127153. Epub 2022 Apr 11.

Authors

Reeta Rani Singhania¹, Anil Kumar Patel¹, Anusuiya Singh², Dibyajyoti Haldar³, Shveta Soam⁴, Chiu-Wen Chen⁵, Mei-Ling Tsai⁶, Cheng-Di Dong⁷

Affiliations

¹ Department of Marine Environmental Engineering, National Kaohsiung University of Science and Technology, Kaohsiung City, Taiwan; Centre for Energy and Environmental Sustainability, Lucknow 226 029, India.
² Department of Marine Environmental Engineering, National Kaohsiung University of Science and Technology, Kaohsiung City, Taiwan.
³ Department of Biotechnology, Karunya Institute of Technology and Sciences, Coimbatore, Tamil Nadu 641114, India.
⁴ Department of Building Engineering, Energy Systems and Sustainability Science, University of Gävle, Kungsbäcksvägen 47, 80176 Gävle, Sweden.
⁵ Department of Marine Environmental Engineering, National Kaohsiung University of Science and Technology, Kaohsiung City, Taiwan; Institute of Aquatic Science and Technology, National Kaohsiung University of Science and Technology, Kaohsiung City, Taiwan.
⁶ Department of Seafood Science, National Kaohsiung University of Science and Technology, Kaohsiung City, Taiwan.
⁷ Department of Marine Environmental Engineering, National Kaohsiung University of Science and Technology, Kaohsiung City, Taiwan; Institute of Aquatic Science and Technology, National Kaohsiung University of Science and Technology, Kaohsiung City, Taiwan. Electronic address: cddong@nkust.edu.tw.

PMID: 35421566
DOI: 10.1016/j.biortech.2022.127153

Abstract

Consolidated bioprocessing (CBP) is characterized by a single-step production of value-added compounds directly from biomass in a single vessel. This strategy has the capacity to revolutionize the whole biorefinery concept as it can significantly reduce the infrastructure input and use of chemicals for various processing steps which can make it economically and environmentally benign. Although the proof of concept has been firmly established in the past, commercialization has been limited due to the low conversion efficiency of the technology. Either a native single microbe, genetically modified microbe or a consortium can be employed. The major challenge in developing a cost-effective and feasible CBP process is the recognition of bifunctional catalysts combining the capability to use the substrates and transform them into value-added products with high efficiency. This article presents an in-depth analysis of the current developments in CBP around the globe and the possibilities of advancements in the future.

Keywords: Bioenergy; Bioethanol; Cellulase; Consolidate bioprocessing; Lignocellulosic biomass.

Publication types

Review

MeSH terms

Biofuels
Biomass
Fermentation
Lignin* / metabolism
Technology*

Substances

Biofuels
lignocellulose
Lignin