Evidence for Anticancer Effects of Chinese Medicine Monomers on Colorectal Cancer

Chin J Integr Med. 2022 Oct;28(10):939-952. doi: 10.1007/s11655-022-3466-2. Epub 2022 Apr 13.

Abstract

Colorectal cancer is one of the most commonly occurring cancers worldwide. Although clinical reports have indicated the anticancer effects of Chinese herbal medicine, the multiple underlying molecular and biochemical mechanisms of action remain to be fully characterized. Chinese medicine (CM) monomers, which are the active components of CM, serve as the material basis of the functional mechanisms of CM. The aim of this review is to summarize the current experimental evidence from in vitro, in vivo, and clinical studies for the effects of CM monomers in colorectal cancer prevention and treatment, providing some useful references for future research.

Keywords: Chinese medicine; anticancer effect; colorectal cancer; experimental evidence; monomer.

Publication types

  • Review

MeSH terms

  • Colorectal Neoplasms* / drug therapy
  • Drugs, Chinese Herbal* / chemistry
  • Drugs, Chinese Herbal* / pharmacology
  • Drugs, Chinese Herbal* / therapeutic use
  • Humans
  • Medicine, Chinese Traditional

Substances

  • Drugs, Chinese Herbal