The aim of the work was a comparative analysis of scientific sources, covering current surgical approaches in the treatment of thymus tumors, as well as the analysis of the results of own experience in minimally invasive surgery for thymus neoplasm. Thymic hyperplasia include tumor-like disorders, cysts and thymic tumors, the latter compose for 60-90% of all thymic lesions. Over the past ten years, due to the development of technologies, a new trends of surgical treatment of thymic tumors has been proposed - minimally invasive techniques, which all over the world changes the historical dogmas concerning thymus surgery, since associated with shorter hospital stays, less intraoperative bleeding, the best aesthetic outcomes. There are four key problems are discussed in thymus surgery today: the role of minimally invasive surgery, the role of lymph node dissection, extension of resection in the case of nonmyasthenic thymoma, treatment of locally advanced tumors of the thymus with pleural defeats. A retro- and prospective analysis of the results of minimally invasive surgery was carried out in 18 patients with thymic tumors in our research, who received surgical therapy during 2018 and 2021 in the department of thoracic surgery (,,New Hospitals", Tbilisi, Georgia). The average age of patients was 51.4±13.2 (M±SD), 3 men (22.2%), 15 women (77.8%). All patients were performed thymectomy by videothoracoscopic method, there were no postoperative crises of myasthenia gravis and other complications in any case. Research results demonstrate high efficiency minimally invasive thymus surgery in clinic practice, which be of help to optimal management and allows to reduce the socio-economic loading on health service.