Antimicrobial stewardship capacity and infection prevention and control assessment of three health facilities in the Ashanti Region of Ghana

Obed Kwabena Offe Amponsah; Alex Owusu-Ofori; Nana Kwame Ayisi-Boateng; Joseph Attakorah; Mercy Naa Aduele Opare-Addo; Kwame Ohene Buabeng

doi:10.1093/jacamr/dlac034

Antimicrobial stewardship capacity and infection prevention and control assessment of three health facilities in the Ashanti Region of Ghana

JAC Antimicrob Resist. 2022 Apr 9;4(2):dlac034. doi: 10.1093/jacamr/dlac034. eCollection 2022 Apr.

Authors

Obed Kwabena Offe Amponsah¹, Alex Owusu-Ofori^{2

3}, Nana Kwame Ayisi-Boateng^{3

4}, Joseph Attakorah¹, Mercy Naa Aduele Opare-Addo¹, Kwame Ohene Buabeng¹

Affiliations

¹ Department of Pharmacy Practice, Faculty of Pharmacy and Pharmaceutical Sciences, College of Health Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
² Department of Microbiology, Komfo Anokye Teaching Hospital, Kumasi, Ghana.
³ School of Medicine and Dentistry, College of Health Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
⁴ University Hospital, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.

Abstract

Background: Addressing antimicrobial resistance (AMR) requires the rational use and optimization of available resources for prevention and management of infections. Structures in health facilities to support optimal antimicrobial therapy and AMR containment therefore need assessment and strengthening.

Objectives: To assess antimicrobial stewardship (AMS) capacity and conformance to National and WHO Infection Prevention and Control (IPC) guidelines in three hospitals in Ashanti region of Ghana.

Methods: A cross-sectional study using WHO's hospital questionnaire for AMS capacity assessment, and Infection Prevention and Control Framework (IPCAF) to assess IPC practices in the three hospitals.

Results: All the facilities had Drug and Therapeutics and IPC Committees with microbiology laboratory services. H3 and H1 did not have a formal AMS programme or an organizational structure for AMS. However, both institutions had a formal procedure to review antibiotics on prescriptions for quality assessment and relevance. H2 and H1 did not participate in any surveillance of antibiotic resistance patterns or consumption. H1 had basic, while H2 and H3 had intermediate-level IPC systems scoring 385, 487.5 and 435.8 out of 800 respectively.

Conclusions: All the facilities assessed had AMS capacity and IPC conformity gaps that require strengthening to optimize antimicrobial use (AMU) and successful implementation of IPC protocols. Regular surveillance of antimicrobial consumption and microbial resistance patterns should be an integral part of activities in health institutions to generate evidence for impactful actions to contain AMR and improve AMU.