The great imposter: A case report of IgG4-RD hypertrophic pachymeningitis with skull lytic lesion and pulmonary nodules

Muhammad Faisal Wadiwala; Liaquat Ali; Adnan Khan; Mohammad Alhatou

doi:10.1002/ccr3.5470

The great imposter: A case report of IgG4-RD hypertrophic pachymeningitis with skull lytic lesion and pulmonary nodules

Clin Case Rep. 2022 Apr 4;10(4):e05470. doi: 10.1002/ccr3.5470. eCollection 2022 Apr.

Authors

Muhammad Faisal Wadiwala¹, Liaquat Ali², Adnan Khan³, Mohammad Alhatou^{1

2}

Affiliations

¹ Neurology Section Al Khor Hospital Hamad Medical Corporation Doha Qatar.
² Neurology Department and Neuroscience Institute Hamad Medical Corporation Doha Qatar.
³ Research Division Department of Medicine Weill Cornell Medicine-Qatar Doha Qatar.

Abstract

Immunoglobulin G4-related disease (Ig4RD) is an inflammatory condition with unique clinical, serological, and pathological features. In this study, we report a challenging diagnostic clinical case of Ig4RD diagnosed based on histopathology. This unique imitating nature reinforces that it is crucial to consider the diagnosis of IgG4-RD in those presenting with pachymeningitis.

Keywords: hypertrophic pachymeningitis; immunoglobulin G4‐related disease; lung nodules; seizures; skull lytic lesion; subdural hematoma.

Publication types

Case Reports