Insect growth regulators with hydrazide moiety inhibit strigolactone biosynthesis in rice

Kojiro Kawada; Yasuyuki Sasaki; Tadao Asami; Shunsuke Yajima; Shinsaku Ito

doi:10.1584/jpestics.D21-063

Insect growth regulators with hydrazide moiety inhibit strigolactone biosynthesis in rice

J Pestic Sci. 2022 Feb 20;47(1):43-46. doi: 10.1584/jpestics.D21-063.

Authors

Kojiro Kawada¹, Yasuyuki Sasaki¹, Tadao Asami², Shunsuke Yajima¹, Shinsaku Ito¹

Affiliations

¹ Department of Bioscience, Tokyo University of Agriculture, Setagaya, Tokyo 156-8502, Japan.
² Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo, Tokyo 113-8657, Japan.

Abstract

Strigolactones (SLs) are carotenoid-derived plant hormones involved in several growth and developmental processes. Also, SLs are allelochemicals that induce the seed germination of root parasitic plants and the hyphal branching of arbuscular mycorrhizal fungi. In this study, to identify novel lead chemicals that inhibit SL biosynthesis, we evaluated the effect of agrochemicals on SL biosynthesis. We found that the diacylhydrazine insect growth regulator, chromafenozide, reduced the endogenous level of 4-deoxyorobanchol (4DO), a major SL in rice. Furthermore, treatment with the same class of insect growth regulator, methoxyfenozide, also resulted in the reduction of 4DO levels in rice root exudates. These results suggest that chromafenozide and methoxyfenozide are novel lead inhibitors of SL biosynthesis.

Keywords: insect growth regulator; rice; screening; strigolactone biosynthesis inhibitor.

© Pesticide Science Society of Japan 2022. This is an open access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) License (https://creativecommons.org/licenses/by-nc-nd/4.0/).