Body Composition Before and After Heart or Lung Transplantation: Preliminary Results

Transplant Proc. 2022 May;54(4):1070-1073. doi: 10.1016/j.transproceed.2022.02.029. Epub 2022 Apr 9.

Abstract

Little is known about the importance of changes in body composition of patients before and after heart or lung transplantation. Reduced muscle mass may be a poor prognostic factor for death and morbidity in patients after orthotopic heart transplantation. Only a few studies have shown data on changes in the amount of adipose tissue and muscle tissue and their impact on patient prognosis. Therefore, more data is needed concerning this issue. The aim of this study was to assess the body composition of patients before and after heart or lung transplantation using bioimpedance. Forty-two patients have been recruited to the study, including 20 patients before organ transplant, 11 patients after heart transplant, and 11 patients after lung transplant (up to 24 months after organ transplantation). The mean age of patients enrolled in the study before and after organ transplantation was 52.05 ± 16.24 years and 50.77 ± 13.38 years, respectively. Body composition measurements were performed by bioimpedance using the SECA mBCA 515 - medical Body Composition Analyzer. In summary, we have shown that body composition was significantly changed after heart and lung transplantation, such as in muscle mass value and fat-free mass value. Adequate intervention at these points might reduce the risk of short and long-term mortality and morbidity.

MeSH terms

  • Adipose Tissue
  • Adult
  • Aged
  • Body Composition
  • Heart Transplantation* / adverse effects
  • Humans
  • Lung Transplantation* / adverse effects
  • Middle Aged
  • Organ Transplantation*