Acute coronary syndrome in patients with cancer

Expert Rev Cardiovasc Ther. 2022 Apr;20(4):275-290. doi: 10.1080/14779072.2022.2063840.

Abstract

Introduction: Improvement in cancer survival has led to an increased focus on cardiovascular disease as the other major determinant of survivorship. As a result, there has been an increasing interest in managing cardiovascular disease during and post cancer treatment.

Areas covered: This article reviews the current literature on the pathogenesis, risk factors, presentation, treatment and clinical outcomes of acute coronary syndrome (ACS) in patients with cancer.

Expert opinion: There is growing evidence that both medical therapy and invasive management of ACS improve outcomes in patients with cancer. Appropriate patient selection, risk stratification and tailored therapy represents the cornerstone of management in these patients.

Keywords: ACS; Acute coronary syndrome; CAD; cancer; chemotherapy; coronary artery disease; myocardial infarction; radiation therapy.

Publication types

  • Review

MeSH terms

  • Acute Coronary Syndrome* / therapy
  • Humans
  • Neoplasms* / complications
  • Neoplasms* / therapy
  • Risk Assessment
  • Risk Factors