Aptamer blocking S-TLR4 interaction selectively inhibits SARS-CoV-2 induced inflammation

Signal Transduct Target Ther. 2022 Apr 11;7(1):120. doi: 10.1038/s41392-022-00968-2.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aptamers, Nucleotide* / genetics
  • Aptamers, Nucleotide* / pharmacology
  • COVID-19*
  • Humans
  • Inflammation / drug therapy
  • Inflammation / genetics
  • SARS-CoV-2
  • Toll-Like Receptor 4 / genetics

Substances

  • Aptamers, Nucleotide
  • TLR4 protein, human
  • Toll-Like Receptor 4