Metallodrugs: Mechanisms of Action, Molecular Targets and Biological Activity

Giarita Ferraro; Antonello Merlino

doi:10.3390/ijms23073504

Metallodrugs: Mechanisms of Action, Molecular Targets and Biological Activity

Int J Mol Sci. 2022 Mar 23;23(7):3504. doi: 10.3390/ijms23073504.

Authors

Giarita Ferraro¹, Antonello Merlino¹

Affiliation

¹ Department of Chemical Sciences, University of Naples Federico II, Complesso Universitario di Monte Sant'Angelo, Via Cinthia 21, I-80126 Naples, Italy.

Abstract

The research interest in the field of inorganic medicinal chemistry had a large increase after the serendipitous discovery of the cytotoxic activity of cisplatin by Rosenberg at the end of 1960s [...].

Publication types

Editorial

MeSH terms

Antineoplastic Agents* / chemistry
Antineoplastic Agents* / pharmacology
Antineoplastic Agents* / therapeutic use
Cisplatin / pharmacology

Substances

Antineoplastic Agents
Cisplatin