On-site illicit-drug detection with an integrated near-infrared spectral sensor: A proof of concept

Talanta. 2022 Aug 1:245:123441. doi: 10.1016/j.talanta.2022.123441. Epub 2022 Apr 5.

Abstract

Illicit-drug production, trafficking and seizures are on an all-time high. This consequently raises pressure on investigative authorities to provide rapid forensic results to assist law enforcement and legal processes in drug-related cases. Ideally, every police officer is equipped with a detector to reliably perform drug testing directly at the incident scene. Such a detector should preferably be small, portable, inexpensive and shock-resistant but should also provide sufficient selectivity to prevent erroneous identifications. This study explores the concept of on-site drugs-of-abuse detection using a 1.8 × 2.2 mm2 multipixel near-infrared (NIR) spectral sensor that potentially can be integrated into a smartphone. This integrated sensor, based on an InGaAs-on-silicon technology, exploits an array of resonant-cavity enhanced photodetectors without any moving parts. A 100% correct classification of 11 common illicit drugs, pharmaceuticals and adulterants was achieved by chemometric modelling of the response of 15 wavelength-specific pixels. The performance on actual forensic casework was investigated on 246 cocaine-suspected powders and 39 MDMA-suspected ecstasy tablets yielding an over 90% correct classification in both cases. These findings show that presumptive drug testing by miniaturized spectral sensors is a promising development ultimately paving the way for a fully integrated drug-sensor in mobile communication devices used by law enforcement.

Keywords: Forensic on-scene analysis; Illicit-drug detection; Indicative testing; Integrated photonics; Portable devices; Spectral sensing.

MeSH terms

  • Cocaine*
  • Illicit Drugs*
  • N-Methyl-3,4-methylenedioxyamphetamine*
  • Smartphone
  • Substance Abuse Detection

Substances

  • Illicit Drugs
  • Cocaine
  • N-Methyl-3,4-methylenedioxyamphetamine