Update on Cutaneous Signs to Assist in the Diagnosis of Dermatomyositis

Curr Rheumatol Rep. 2022 May;24(5):156-165. doi: 10.1007/s11926-022-01070-w. Epub 2022 Apr 11.

Abstract

Purpose of review: Dermatomyositis (DM) is a heterogeneous idiopathic inflammatory myopathy that can be challenging to diagnose. Learning about the cutaneous manifestations in DM can assist with prompt diagnosis as well as subgroup classification. This review highlights recent data regarding cutaneous signs in DM and their associations with myositis-specific antibodies (MSAs).

Recent findings: Several novel DM skin signs have recently been reported. Novel and confirmatory data have helped to define more clearly the associations between various cutaneous manifestations and MSAs. Awareness of the diverse cutaneous phenotypes can help with the timely diagnosis of DM. As some MSAs are associated with atypical skin features and/or characteristic patterns of clinical findings, knowledge of these associations can help clinicians to recognize DM patients. Understanding how the prevalence and presentation of various cutaneous signs differ among ethnically diverse patients is a high priority for further study.

Keywords: Cutaneous signs; Dermatomyositis (DM); Myositis-specific antibodies (MSAs); Novel signs; Patients of color; This article is part of the Topical Collection on Inflammatory Muscle Disease.

Publication types

  • Review

MeSH terms

  • Autoantibodies
  • Dermatomyositis*
  • Humans
  • Myositis*
  • Phenotype
  • Skin

Substances

  • Autoantibodies