Objective: To observe the clinical therapeutic effect of CO2 laser moxibustion on endometriosis related pelvic pain of cold coagulation and blood stasis.
Methods: A total of 76 patients with endometriosis related pelvic pain of cold coagulation and blood stasis were randomized into a laser moxibustion group and a sham laser moxibustion group, 38 cases in each group. In the laser moxibustion group, moxibustion was applied at bilateral Zigong (EX-CA 1) using CO2 laser moxibustion instrument. In the sham laser moxibustion group, the manipulation of moxibustion was same as the laser moxibustion group, without laser output. The treatment was given once every other day, 30 min each time, 3 times a week for 4 weeks in both groups. Before and after treatment and follow-up of 3 months after treatment, the scores of Gracely box scale (GBS) and visual analogue scale (VAS) were observed, the usage of non-steroidal anti-inflammatory drug for the duration of the treatment and the average days of taking drugs were recorded in both groups.
Results: Compared before treatment, the GBS and VAS scores were decreased after treatment and during follow-up in the laser moxibustion group (P<0.05), while those in the sham moxibustion group had no significant differences (P>0.05). Compared with the sham moxibustion group, the GBS and VAS scores were decreased after treatment and during follow-up (P<0.05), the cases and average days of taking drugs were less in the laser moxibustion group (P<0.05).
Conclusion: CO2 laser moxibustion can improve the pain symptom in patients with endometriosis related pelvic pain of cold coagulation and blood stasis, and reduce the use of analgesic drugs.
目的：观察CO2激光灸治疗寒凝血瘀型子宫内膜异位症（EMs）关联盆腔疼痛的临床疗效。方法：将76例寒凝血瘀型EMs关联盆腔疼痛患者随机分为激光灸组和假激光灸组，每组38例。激光灸组采用CO2激光灸疗仪于双侧子宫穴施灸；假激光灸组与激光灸组操作一致，但无任何激光输出。两组均隔日治疗1次，每次30 min，每周治疗3次，共计4周。分别于治疗前、治疗后及治疗后3个月随访观察两组患者Gracely box scale（GBS）评分、视觉模拟量表（VAS）评分，并记录两组患者治疗期间非甾体抗炎药物使用情况及平均用药天数。结果：与治疗前比较，激光灸组治疗后、随访GBS评分、VAS评分均降低（P<0.05），假激光灸组治疗后、随访GBS评分、VAS评分差异无统计学意义（P>0.05）；激光灸组治疗后、随访GBS评分、VAS评分低于假激光灸组（P<0.05）。激光灸组较假激光灸组合并用药人次及平均用药天数少（P<0.05）。结论：CO2激光灸能改善寒凝血瘀型EMs关联盆腔疼痛患者疼痛症状，减少镇痛药物的使用。.
Keywords: Point EX-CA 1 (Zigong); cold coagulation and blood stasis; endometriosis; laser moxibustion; pelvic pain; randomized controlled trial (RCT).