Mountain Ultra-Marathon (UTMB) Impact on Usual and Emerging Cardiac Biomarkers

Caroline Le Goff; Laurent Gergelé; Laurence Seidel; Etienne Cavalier; Jean-François Kaux

doi:10.3389/fcvm.2022.856223

Mountain Ultra-Marathon (UTMB) Impact on Usual and Emerging Cardiac Biomarkers

Front Cardiovasc Med. 2022 Mar 24:9:856223. doi: 10.3389/fcvm.2022.856223. eCollection 2022.

Authors

Caroline Le Goff¹, Laurent Gergelé², Laurence Seidel³, Etienne Cavalier¹, Jean-François Kaux^{4

5}

Affiliations

¹ Department of Clinical Chemistry, University Hospital of Liege and University of Liège, Liège, Belgium.
² Department of Intensive Care, Intensive Unit Care, University Hospital of Saint Etienne, University of Lyon, Lyon, France.
³ Biostatistics Department, University Hospital of Liege, Liège, Belgium.
⁴ Department of Sports and Rehabilitation Sciences, University of Liège, Liège, Belgium.
⁵ Physical Medicine and Sport Traumatology Department, SportS2, IOC Research Centre for Prevention of Injury and Protection of Athlete Health FIFA Medical Centre of Excellence, FIMS Collaborative Centre of Sports Medicine, University Hospital of Liège, Liège, Belgium.

Abstract

The number of participants in ultra-marathons is increasing. However, the data regarding the impact of this type of exercise on the cardiovascular system are contradictory. In our study, 28 ultra-trail runners were enrolled. Blood samples were collected at three time points: immediately before, immediately after, and 7 days after the ultra-marathon. Different biomarkers were measured. Immediately after the race, the blood concentrations of the different cardiac and inflammatory biomarkers increased significantly. Interestingly, some biomarkers remained high even after 7 days of recovery.

Keywords: H-FABP; ST2; cardiac biomarker; copeptin; troponin; ultra-trail.