A Large Cavernous Sinus Giant Cell Tumor Invading Clivus and Sphenoid Sinus Masquerading as Meningioma: A Case Report and Literature Review

Shasha Hu; Shaowen Cheng; Yu Wu; Yanyan Wang; XinNian Li; Jiaxuan Zheng; Jiao Li; Lei Peng; Jian Yang

doi:10.3389/fsurg.2022.861739

A Large Cavernous Sinus Giant Cell Tumor Invading Clivus and Sphenoid Sinus Masquerading as Meningioma: A Case Report and Literature Review

Front Surg. 2022 Mar 24:9:861739. doi: 10.3389/fsurg.2022.861739. eCollection 2022.

Authors

Shasha Hu¹, Shaowen Cheng^{2

3

4}, Yu Wu¹, Yanyan Wang¹, XinNian Li¹, Jiaxuan Zheng¹, Jiao Li¹, Lei Peng^{2

4}, Jian Yang^{2

3

4}

Affiliations

¹ Department of Pathology, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University, Haikou, China.
² Trauma Center, The First Affiliated Hospital of Hainan Medical University, Haikou, China.
³ Department of Wound Repair, First Affiliated Hospital of Hainan Medical University, Haikou, China.
⁴ Key Laboratory of Emergency and Trauma Ministry of Education, Hainan Medical University, Haikou, China.

Abstract

Giant cell tumor (GCT) of the bone is a rare benign, locally aggressive tumor that occurs in the epiphysis of long bones, especially the lower femur and the upper tibia. GCT of the bone of cranial origin is very rare, accounting for 1% of all GCT of the bone. We report the diagnosis, treatment, and immunohistochemistry of a rare case of intracranial GCT of the bone. We also review and summarize the imaging features, diagnostic markers, and current major treatment options for GCT of the bone. Our case and literature review emphasizes the importance of considering the full picture when making a diagnosis, rather than relying on imaging alone to make the diagnosis.

Keywords: case report; cavernous sinus; clivus; giant cell tumors; sphenoid sinus.

Publication types

Case Reports