Role of glycated proteins in vivo: Enzymatic glycated proteins and non-enzymatic glycated proteins

Abstract

Glycated protein is a kind of substance that often exists in the human body through the combination of sugar and protein under enzyme or non-enzyme conditions. Enzyme-catalyzed glycated proteins are widely distributed in the human body and participate in life activities such as human growth and immune regulation. Non-enzymatic glycated protein is often related to cancer, aging, diabetes and other diseases, but in vitro non-enzymatic glycated protein has utility value after modification. This review not only discussed the effects of enzymatic glycated protein on human intestinal health, immune regulation and cancer prevention. The inhibition methods of non-enzymatic glycated protein in food processing, digestion, absorption and metabolism were also elucidated.

Keywords: Enzymatic glycation; Harm; Health; Inhibit; Non-enzymatic glycation.