Recent advances in biomedical applications of 2D nanomaterials with peroxidase-like properties

Adv Drug Deliv Rev. 2022 Jun:185:114269. doi: 10.1016/j.addr.2022.114269. Epub 2022 Apr 6.

Abstract

Significant progress has been made in developing two-dimensional (2D) nanomaterials owing to their ultra-thin structure, high specific surface area, and many other advantages. Recently, 2D nanomaterials with enzyme-like properties, especially peroxidase (POD)-like activity, are highly desirable for many biomedical applications. In this review, we first classify the types of 2D POD-like nanomaterials and then summarize various strategies for endowing 2D nanomaterials with POD-like properties. Representative examples of biomedical applications are reviewed, emphasizing in antibacterial, biosensing, and cancer therapy. Last, the future challenges and prospects of 2D POD-like nanomaterials are discussed. This review is expected to provide an in-depth understanding of 2D POD-like materials for biomedical applications.

Keywords: 2D nanomaterials; Biomedical applications; Enzyme-like; Peroxidase.

Publication types

  • Review

MeSH terms

  • Humans
  • Nanostructures* / chemistry
  • Peroxidase*
  • Peroxidases

Substances

  • Peroxidases
  • Peroxidase