Phyto-mediated synthesis of nanoparticles and their applications on hydrogen generation on NaBH4, biological activities and photodegradation on azo dyes: Development of machine learning model

Junqing Lin; Fulya Gulbagca; Aysenur Aygun; Rima Nour Elhouda Tiri; Changlei Xia; Quyet Van Le; Tugba Gur; Fatih Sen; Yasser Vasseghian

doi:10.1016/j.fct.2022.112972

Phyto-mediated synthesis of nanoparticles and their applications on hydrogen generation on NaBH₄, biological activities and photodegradation on azo dyes: Development of machine learning model

Food Chem Toxicol. 2022 May:163:112972. doi: 10.1016/j.fct.2022.112972. Epub 2022 Apr 6.

Authors

Junqing Lin¹, Fulya Gulbagca², Aysenur Aygun², Rima Nour Elhouda Tiri², Changlei Xia³, Quyet Van Le⁴, Tugba Gur⁵, Fatih Sen⁶, Yasser Vasseghian⁷

Affiliations

¹ Department of Interventional Radiology, Fujian Medical University Union Hospital, Fuzhou, 350001, China. Electronic address: junqlin@163.com.
² Sen Research Group, Biochemistry Department, Faculty of Arts and Science, Dumlupinar University, Evliya Celebi Campus, 43100, Kutahya, Turkey.
³ Jiangsu Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, International Innovation Center for Forest Chemicals and Materials, College of Materials Science and Engineering, Nanjing Forestry University, Nanjing, Jiangsu, 210037, China.
⁴ Department of Materials Science and Engineering, Institute of Green Manufacturing Technology, Korea University, 145, Anam-ro, Seongbuk-gu, Seoul, 02841, South Korea.
⁵ Vocational School of Health Services, Van Yuzuncu Yil University, 65090, Van, Turkey.
⁶ Sen Research Group, Biochemistry Department, Faculty of Arts and Science, Dumlupinar University, Evliya Celebi Campus, 43100, Kutahya, Turkey. Electronic address: fatih.sen@dpu.edu.tr.
⁷ Department of Chemistry, Soongsil University, Seoul, 06978, South Korea; The University of Johannesburg, Department of Chemical Engineering, P.O. Box 17011, Doornfontein 2088, South Africa; Department of Chemical Engineering, Quchan University of Technology, Quchan, Iran. Electronic address: vasseghian@ssu.ac.kr.

PMID: 35398181
DOI: 10.1016/j.fct.2022.112972

Abstract

This work reports the synthesis of the silver-platinum bimetallic nanoparticles (N@Pt-Ag BNPs) reduced by an ethanolic extract of black seed (Nigella sativa, N) using the green synthesis method, these nanoparticles show a great antibacterial, anticancer, and catalytic activity. The characterization of physicochemical properties of Ag-Pt BNP was carried out using UV-visible spectroscopy (Uv-vis), Fourier-transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), and Transmission electron microscope (TEM) analysis. The structural morphology shows that the N@Pt-Ag BNPs are spherical particles with a diameter of 5.6 nm. The cytotoxic effects of N@Pt-Ag BNPs were examined by MTT test in human breast cancer, human colon cancer, human pancreatic cancer, L929-Murine fibroblast cells. N@Pt-Ag BNPs have been observed to be much more effective in breast cancer cell lines. The cytotoxic effect of N@Pt-Ag BNPs against healthy L929-murine fibroblast cell lines was not observed. Also, high antibacterial activity on each of the bacteria Escherichia coli (E. coli), Bacillus subtilis (B. subtilis), Methicillin-resistant Staphylococcus aureus (MRSA), Staphylococcus aureus (S. aureus), where we note that most strains of E. coli and S. aureus were damaged with a 73% percentage, 67% bacterial inhibition respectively. The results of the catalytic activities of N@Pt-Ag BNPs were obtained by performing the hydrolysis experiments of sodium borohydride (NaBH₄). According to the results obtained, TOF, enthalpy, entropy, and activation energy, values were found to be 2497.14 h^-1, 13.52 kJ/mol, -137.47 J/mol.K, 16.02 kJ/mol, respectively. N@Pt-Ag BNPs were found to be highly effective catalysts for hydrogen production which this was also confirmed by the machine learning model. The photocatalytic activity of N@Pt-Ag BNPs was tested against methylene blue (MB) dye and the highest activity was found as 80%.

Keywords: Antibacterial activity; Anticancer activity; Hydrogen production; Machine learning; Photocatalytic activity; Silver-Platinum bimetallic nanoparticles.

MeSH terms

Animals
Anti-Bacterial Agents / chemistry
Anti-Bacterial Agents / pharmacology
Azo Compounds / pharmacology
Escherichia coli
Humans
Hydrogen / pharmacology
Machine Learning
Metal Nanoparticles* / chemistry
Metal Nanoparticles* / toxicity
Methicillin-Resistant Staphylococcus aureus*
Mice
Photolysis
Silver / chemistry
Silver / pharmacology
Spectroscopy, Fourier Transform Infrared
Staphylococcal Infections*
Staphylococcus aureus
X-Ray Diffraction

Substances

Anti-Bacterial Agents
Azo Compounds
Silver
Hydrogen