Giant cell arteritis associated with acute Q fever - A case report

J Infect Chemother. 2022 Aug;28(8):1177-1179. doi: 10.1016/j.jiac.2022.03.028. Epub 2022 Apr 6.

Abstract

Q fever is a worldwide spread zoonotic disease, caused by the gram-negative intracellular bacillus Coxiella burnetii. Apart from its most common manifestations, Q fever has been reported to occasionally mimic autoimmune diseases. We herein present a case of acute Q fever in a 69-year-old man, manifesting as prolonged fever with pneumonitis, in whom biopsy of the temporal artery revealed giant cell arteritis. Moreover, PCR testing of the biopsy specimen was positive for Coxiella burnetii, thus further supporting the possibly infectious etiology of some cases of biopsy proven giant cell arteritis, with implications for treatment.

Keywords: Coxiella burnetii; Giant cell arteritis; Q fever; Temporal arteritis.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Coxiella burnetii* / genetics
  • Giant Cell Arteritis* / complications
  • Giant Cell Arteritis* / diagnosis
  • Humans
  • Male
  • Polymerase Chain Reaction
  • Q Fever* / complications
  • Q Fever* / diagnosis
  • Q Fever* / drug therapy