Renal cell carcinoma uvula metastasis leading to airway compromise: an unusual site

BMJ Case Rep. 2022 Apr 8;15(4):e248098. doi: 10.1136/bcr-2021-248098.

Abstract

We present a case report of a gentleman presenting with a globular lesion arising from his uvula. Although elective admission was planned, he presented with airway compromise, and emergency excision was required. The patient had a background of metastatic clear cell renal carcinoma; histology confirmed the uvula lesion as a further secondary deposit. Renal cell carcinoma has a recognised metastatic propensity, but spread to the uvula is rare, with only two previously described cases in the literature. This case is notable for the unusual location of the metastasis, as well as the rapid progression of symptoms, which threatened the airway and necessitated urgent surgical intervention.

Keywords: Head and neck cancer; Otolaryngology / ENT; Pathology; Urological cancer.

Publication types

  • Case Reports

MeSH terms

  • Carcinoma, Renal Cell* / surgery
  • Humans
  • Kidney Neoplasms* / pathology
  • Kidney Neoplasms* / surgery
  • Lung Diseases, Obstructive*
  • Male
  • Uvula / pathology