HER2-Negative Schnitzler Metastasis to the Rectum Detected Using 18 F-FDG PET/CT

Clin Nucl Med. 2022 Sep 1;47(9):826-827. doi: 10.1097/RLU.0000000000004208. Epub 2022 Apr 6.

Abstract

Gastric carcinoma metastasis occurs via hematogenous, lymphatic, or peritoneal seeding. We describe FDG PET/CT findings of Schnitzler metastasis to the rectum in a 39-year-old woman who had radical gastrectomy for signet ring gastric adenocarcinoma 2 years prior. FDG PET/CT demonstrated increased homogeneous round activity in the inner layer of rectal wall. Occult metastases of gastric carcinoma tend to be difficult to treat and have a poor prognosis. However, in some cases, FDG PET/CT might be beneficial for early detection and diagnosis of Schnitzler metastasis.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Carcinoma*
  • Female
  • Fluorodeoxyglucose F18
  • Humans
  • Positron Emission Tomography Computed Tomography
  • Radiopharmaceuticals
  • Rectum / pathology
  • Stomach Neoplasms* / diagnostic imaging
  • Stomach Neoplasms* / pathology

Substances

  • Radiopharmaceuticals
  • Fluorodeoxyglucose F18