New developments in neonatal respiratory management

I-Ling Chen; Hsiu-Lin Chen

doi:10.1016/j.pedneo.2022.02.002

New developments in neonatal respiratory management

Pediatr Neonatol. 2022 Jul;63(4):341-347. doi: 10.1016/j.pedneo.2022.02.002. Epub 2022 Mar 16.

Authors

I-Ling Chen¹, Hsiu-Lin Chen²

Affiliations

¹ Department of Respiratory Therapy, College of Medicine, Kaohsiung Medical University, No. 100, Shih-Chuan 1st Road, San Ming District, Kaohsiung, Taiwan.
² Department of Respiratory Therapy, College of Medicine, Kaohsiung Medical University, No. 100, Shih-Chuan 1st Road, San Ming District, Kaohsiung, Taiwan; Department of Pediatrics, Kaohsiung Medical University Hospital, No. 100, Tzyou 1st Road, San Ming District, Kaohsiung, Taiwan. Electronic address: ch840062@kmu.edu.tw.

PMID: 35382987
DOI: 10.1016/j.pedneo.2022.02.002

Abstract

Respiratory distress syndrome (RDS) is the major cause of respiratory failure in preterm infants due to immature lung development and surfactant deficiency. Although the concepts and methods of managing respiratory problems in neonates have changed continuously, determining appropriate respiratory treatment with minimal ventilation-induced lung injury and complications is crucially important. This review summarizes neonatal respiratory therapy's advances and available strategies (i.e., exogenous surfactant therapy, noninvasive ventilation, and different ventilation modes), focusing on RDS management.

Keywords: less invasive surfactant administration (LISA); neonates; neurally Adjusted Ventilatory Assist (NAVA); noninvasive Ventilation (NIV); volume guarantee ventilation.

Publication types

Review

MeSH terms

Humans
Infant
Infant, Newborn
Infant, Premature
Interactive Ventilatory Support*
Noninvasive Ventilation*
Respiratory Distress Syndrome, Newborn* / therapy
Surface-Active Agents

Substances

Surface-Active Agents