First report of a gallbladder hemangioma coexisting with gallstones: a case report and literature review of a rare finding

BMC Surg. 2022 Apr 6;22(1):128. doi: 10.1186/s12893-022-01554-7.

Abstract

Background: Gallbladder hemangioma is an exceptionally rare entity, with only ten cases reported in literature hitherto. The here described case is the first report of a gallbladder hemangioma coexisting with gallstones.

Case presentation: A 76-year-old male was hospitalized following repeated episodes of epigastric pain. Patient's medical history included primary hypertension, type 2 diabetes mellitus, dyslipidemia, obesity and hyperuricemia. Physical examination revealed marked pain in the right hypochondriac region, and laboratory workup was notable for mildly elevated glycemia (125 mg/dL) and pancreatic amylase (60 IU/L). Abdominal ultrasound showed multiple gallstones, a thickened gallbladder wall and mild edema of the perivisceral adipose tissue as well as a hepatic angioma. During surgery, an incidental subserosal nodule of about 1 cm was detected within the gallbladder fundus. After surgery, the clinical course was uneventful and the patient was discharged. Histopathological examination of the subserosal nodule showed multiple dilated vascular channels within a sclerosing matrix, a finding consistent with a cavernous hemangioma. Diffuse chronic cholecystitis was also present.

Conclusions: Gallbladder hemangiomas represent a rare, likely underdiagnosed condition which can be undetected during the preoperative workup.

Keywords: Gallbladder; Gallstones; Hemangioma.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aged
  • Cholecystitis* / diagnosis
  • Diabetes Mellitus, Type 2*
  • Gallstones* / complications
  • Gallstones* / diagnosis
  • Gallstones* / surgery
  • Hemangioma* / surgery
  • Humans
  • Male