Surgical Treatment of Ameloblastoma: How Does It Impact the Oral Health-Related Quality of Life? A Systematic Review

Wladimir Gushiken de Campos; Gustavo Luiz Alkmin Paiva; Camilla Vieira Esteves; André Caroli Rocha; Pedro Gomes; Celso Augusto Lemos Júnior

doi:10.1016/j.joms.2022.03.003

Surgical Treatment of Ameloblastoma: How Does It Impact the Oral Health-Related Quality of Life? A Systematic Review

J Oral Maxillofac Surg. 2022 Jun;80(6):1103-1114. doi: 10.1016/j.joms.2022.03.003. Epub 2022 Mar 10.

Authors

Wladimir Gushiken de Campos¹, Gustavo Luiz Alkmin Paiva², Camilla Vieira Esteves³, André Caroli Rocha⁴, Pedro Gomes⁵, Celso Augusto Lemos Júnior⁶

Affiliations

¹ PhD Student, Department of Oral Medicine, Faculdade de Odontologia, Universidade de São Paulo, São Paulo, Brazil. Electronic address: wgushiken@hotmail.com.
² Postgraduate Student, Department of Oral Medicine, Faculdade de Odontologia, Universidade Estadual de Campinas, São Paulo, Brazil.
³ Professor, Department of Oral Medicine, Faculdade de Odontologia, Universidade de São Paulo São Paulo, Brazil.
⁴ Professor, Department of Dentistry, Clinics Hospital, University of Sâo Paulo, São Paulo, Brazil.
⁵ Professor, Laboratory for Bone Metabolism and Regeneration, Faculty of Dental Medicine, University of Porto, Porto, Portugal.
⁶ Professor, Department of Oral Medicine, Faculdade de Odontologia, Universidade de São Paulo, São Paulo, Brazil.

PMID: 35378094
DOI: 10.1016/j.joms.2022.03.003

Abstract

Purpose: This study aimed to analyze the impact of surgical treatment on the quality of life of patients diagnosed with ameloblastoma.

Methods: We searched PubMed, Science Direct, LILACS, EMBASE, and Web of Science, up to February 2021, with no time restriction. We considered only studies published in English that evaluated patients diagnosed with ameloblastoma who underwent conservative or radical surgical treatments using a quality of life (QOL) instrument.

Results: Of the 2155 studies identified, ten were included in our sample. Only studies that analyzed QOL of radical surgical treatment were included. No studies that analyzed QOL after conservative surgical treatment were found. Across all studies, 283 patients (122 females and 161 males; mean age: 28.13 years) were surgically treated for ameloblastoma. A total of 69 complications were reported, with the most frequent being infection in both the donor and recipient site (18 cases) and graft loss (8 cases).

Conclusion: Surgical treatment of ameloblastoma was effective in providing reasonable health-related QOL, as most of the assessed dimensions were found to improve.

Publication types

Review
Systematic Review

MeSH terms

Adult
Ameloblastoma* / surgery
Conservative Treatment
Female
Humans
Male
Quality of Life