Naturally occurring prenylated stilbenoids: food sources, biosynthesis, applications and health benefits

Crit Rev Food Sci Nutr. 2023;63(26):8083-8106. doi: 10.1080/10408398.2022.2056131. Epub 2022 Apr 4.

Abstract

Prenylated stilbenoids are a unique class of natural phenolic compounds consisting of C6-C2-C6 skeleton with prenyl substitution. They are potential nutraceuticals and dietary supplements presented in some edible plants. Prenylated stilbenoids demonstrate promising health benefits, including antioxidant, anti-cancer, anti-inflammatory, anti-microbial activities. This review reports the structure, bioactivity and potential application of prenylated stilbeniods in food industry. Edible sources of these compounds are compiled and summarized. Structure-activity relationship of prenylated stilbenoids are also highlighted. The biosynthesis strategies of prenylated stilbenoids are reviewed. The findings of these compounds as food preservative, nutraceuticals and food additive are discussed. This paper combines the up-to-date information and gives a full image of prenylated stilbenoids.

Keywords: Antioxidant activity; bioactivity; nutraceuticals; resveratrol; structure.

Publication types

  • Review

MeSH terms

  • Anti-Inflammatory Agents / pharmacology
  • Phenols
  • Prenylation
  • Stilbenes*
  • Structure-Activity Relationship

Substances

  • Stilbenes
  • Anti-Inflammatory Agents
  • Phenols