Improvement of pseudophakic cystoid macular edema with subconjunctival injections of interferon α2b:a case report

Hossein Aghaei; Acieh Es'haghi; Rama Pourmatin

doi:10.1016/j.ajoc.2022.101504

Improvement of pseudophakic cystoid macular edema with subconjunctival injections of interferon α2b:a case report

Am J Ophthalmol Case Rep. 2022 Mar 23:26:101504. doi: 10.1016/j.ajoc.2022.101504. eCollection 2022 Jun.

Authors

Hossein Aghaei¹, Acieh Es'haghi^{1

2}, Rama Pourmatin¹

Affiliations

¹ Eye Research Center, The Five Senses Health Institute, Rassoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran.
² Department of Ophthalmology, Imam Hossein Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Abstract

Purpose: To report a patient with resistant cystoid macular edema after an uneventful phacoemulsification cataract surgery who responded to subconjunctival interferon α2b injections.

Observations: This report describes a 60-year-old male patient with pseudophakic cystoid macular edema that was unresponsive to multiple courses of topical non-steroidal anti-inflammatory drugs and steroids during the follow-up period. Weekly subconjunctival interferon α2b (5 MIU/ml) was administered four times. Cystoid macular edema completely resolved after the 4th injection.During a six-month follow-up period, cystoid macular edema did not recur. No adverse local and systemic side effects were observed.

Conclusions and importance: Weekly subconjunctival interferon α2b injections might be a safe and effective treatment modality in the treatment of stubborn pseudophakic cystoid macular edema to conventional treatment.

Keywords: Cataract surgery; Cystoid macular edema; Interferon.

Publication types

Case Reports