Clinical versus radiographical factors associated with hepatocellular carcinoma diagnosis in high-risk patients: sizes matter

Tanita Suttichaimongkol; Manoon Mitpracha; Kawin Tangvoraphonkchai; Phuangphaka Sadee; Kittisak Sawanyawisuth; Wattana Sukeepaisarnjaroen

doi:10.2144/fsoa-2021-0108

Clinical versus radiographical factors associated with hepatocellular carcinoma diagnosis in high-risk patients: sizes matter

Future Sci OA. 2022 Feb 2;8(4):FSO785. doi: 10.2144/fsoa-2021-0108. eCollection 2022 Apr.

Authors

Tanita Suttichaimongkol¹, Manoon Mitpracha², Kawin Tangvoraphonkchai¹, Phuangphaka Sadee¹, Kittisak Sawanyawisuth¹, Wattana Sukeepaisarnjaroen¹

Affiliations

¹ Department of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand.
² Department of Medicine, Division of Gastroenterology, Khon Kaen Regional Hospital, Khon Kaen, 40002, Thailand.

Abstract

Aim: This study aimed to evaluate if clinical or radiographic findings can be used for hepatocellular carcinoma (HCC) diagnosis particularly in high-risk patients.

Methods: This was a prospective study and evaluated factors associated with HCC.

Results: There were 260 patients met the study criteria: 219 patients (84.23%) were HCC. Two factors significantly associated with HCC: portal vein invasion and the largest mass size. The cutoff point for the largest mass size of 2 cm or over gave sensitivity and specificity for HCC of 83.56 and 87.80%, respectively.

Conclusion: Portal vein invasion and the largest liver mass of 2 cm or over may be diagnostic factors for HCC in high-risk patients, while clinical factors were not suggestive for HCC.

Keywords: cirrhosis; hepatitis virus; size.