Advancement in Nanoparticle-based Biosensors for Point-of-care In vitro Diagnostics

Curr Top Med Chem. 2022;22(10):807-833. doi: 10.2174/1568026622666220401160121.

Abstract

Recently, there has been great progress in the field of extremely sensitive and precise detection of bioanalytes. The importance of the utilization of nanoparticles in biosensors has been recognized due to their unique properties. Specifically, nanoparticles of gold, silver, and magnetic plus graphene, quantum dots, and nanotubes of carbon are being keenly considered for utilization within biosensors to detect nucleic acids, glucose, or pathogens (bacteria as well as a virus). Taking advantage of nanoparticles, faster and sensitive biosensors can be developed. Here, we review the nanoparticles' contribution to the biosensors field and their potential applications.

Keywords: Biosensors; Detection; Glucose; In vitro diagnostics; Nanoparticles; Nucleic acids; Pathogens.

Publication types

  • Review

MeSH terms

  • Biosensing Techniques*
  • Gold
  • Nanoparticles*
  • Point-of-Care Systems
  • Quantum Dots*

Substances

  • Gold